GCMS - Gas Chromatography – Mass Spectrometry
Gas chromatography mass spectrometry (GC-MS) is an analytical method that combines the features of gas-chromatography and mass spectrometry to identify different substances within a mixture of components. The components of a test sample are separated by the gas chromatograph and then identified by means of mass spectrometry.
Liquid organic solvents or mixtures can be analyzed directly by GC-MS. The sample is diluted in methanol and a few microliters of this solution are then injected in the liquid injection unit of the GC-MS in which the mixture is separated and the single compounds are analyzed qualitative as well as quantitatively.
Hyphenated Techniques
The coupling of Gas Chromatography with Mass Spectrometry is a powerful tool to characterize complex mixtures of so called volatile organic compounds (VOCs). By use of gas chromatography (GC) these mixtures can be separated into the single compounds. Then the single compounds are quantified and characterized by mass spectrometry. The comparison of the obtained mass spectra to data base spectra opens the potential to identify a vast number of organic substances.
The introduction of the samples into the GC can be handled in various ways, thus enabling a variety of application fields for this analytic technique:
TD-GCMS - Thermo-Desorption Gas Chromatography Mass Spectrometry
TGA-GCMS - Thermo Gravimetric Analysis coupled with Gas Chromatography Mass Spectrometry
TGA-MS – Thermo Gravimetric Analysis coupled with Mass Spectrometry
Applications
- Purity analysis of organic solvents / identification of contaminations
- Screening of organic substances for components after cleaning processes
Technical Specifications
PerkinElmer - CLARUS SQ 8 GC/MS
PerkinElmer - CLARUS 680 (GC without Autosampler)
- Oven temperature: 30°C to 330°C/350°C
- Packed-column injector, 50 ˚C to 330°C/350°C
- Elite-5 Capillary Column - 30 m x 0.25 mm I.D. x 0.25 μm
PerkinElmer - CLARUS SQ 8T (MS)
- Source: PerkinElmer SMARTsource™
- Ionization Type: EI
- Filament: Marathon™
- Mass Range 1.0 – 1,200 u (amu)
- Detector Clarifi™
- Analyzer: Quadrupole with pre-filter
- Temperature Settings SMARTsource: Settable 50 ˚C – 350 ˚C
- GC transfer line: Settable 50 ˚C – 350 ˚C